Personalised medicine: the individual at the centre

In a nutshell, the Personalised Medicine route is pursuing the ideal of making effective care as close to home as possible a reality for every individual patient. To achieve that, advances are needed in the creation of knowledge and in the organisation of care. In addition to major investments in a robust data infrastructure and in technological and methodological developments, new research coalitions and intensive communication with the public are essential.

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Projecten

Minimally invasive techniques in oncology; identification of hurdles towards clinical implementation and support of promising initiatives

For personalised treatment, minimally invasive techniques gather information on patient and disease characteristics, necessary to select

Minimally invasive techniques in oncology: the next steps

For personalised treatment, minimally invasive techniques gather information on patient and disease characteristics, necessary to select

Vraagkracht: Vroegsignalering van syndemische kwetsbaarheid

Cardiometabole aandoeningen, zoals diabetes type 2, komen vaak samen voor met depressie.

Een groene leefomgeving en cardiometabole en respiratoire gezondheid: de complexe relatie met luchtkwaliteit en sociaaleconomische status (LOCATION)

De plek waar je woont beïnvloedt je gezondheid.

DNA cinema

Genetisch onderzoek ontwikkelt zich momenteel razendsnel en er wordt steeds meer mogelijk, zoals het vaststellen van aanleg voor ziekten

Diversiteit verbinden: co-creatie tussen onderzoekers en patiënten met een migratieachtergrond om kennis over wetenschappelijk onderzoek binnen de oncologie en het patiëntenperspectief te vergroten.

Wetenschappelijk onderzoek is het fundament voor goede zorg maar is vaak niet representatief.

SYMPHONY: Orchestrating personalised treatment in patients with bleeding disorders

More than 180.000 children and adults in the Netherlands are affected by an inborn bleeding disorder.

New, rational therapy decisions for developmental brain disorders: Integrating quantitative patient assessment, cellular assays and nanotechnology (NewTDec)

The limited progress in finding adequate therapies for many developmental brain disorders is a frustration for scientists, clinicians and

ProMiSe: Tackling defective Prefrontal development in Mendelian Syndromes - a compelling (pre-)clinical integrative approach

Mendelian neurodevelopmental disorders (NDDs) are collectively common yet individually caused by single mutated genes.

Healthy Loading to combat osteoarthritis: Leveraging molecular variations in load bearing capacity for individualized movement aDvice: The LoaD project

Osteoarthritis, a painful and disabling joint disease, impairs everyday life activities of 1.5 million people in the Netherlands.

NANOSPRESSO-NL: Local preparation of high-quality, personalized nucleic acid nanomedicines

Nucleic acid therapeutics are revolutionizing medicine.

Optimal survival and quality of life in metastatic colorectal cancer with irinotecan dosing based on UGT1A1 genotype and gut microbiome enzyme activity including a dietary intervention. (OPTIMA)

Irinotecan-based systemic therapy is the main chemotherapeutic choice for the treatment of metastatic colorectal cancer (mCRC).

Next generation immunodermatology (NGID)

The development of sophisticated diagnostics and new therapeutics in dermatology has been neglected for a long time.

BiOmarkers tO perSonalise Treatment of depression (BOOST depression)

Depression is the leading cause of disability.

META-IMMUNOTYPES: Decoding immune-metabolic homeostasis to better understand chronic diseases

The immune system is a complex network of cells with a high level of specialization that are distributed through our entire anatomy and h

We cover these questions

Welke vragen hopen we met dit project te beantwoorden? Deze vragen zijn gegroepeerd in de volgende clustervragen.